A Guide to Sample Size for Animal Based Studies

======================================================= A GUIDE TO SAMPLE SIZE FOR ANIMAL BASED STUDIES Professional Veterinary E-Book ======================================================= BOOK INFORMATION ---------------- Title: A Guide to Sample Size for Animal Based Studies Format: PDF E-Book File Size: Varies Category: Veterinary Research Methodology Specialty: Biostatistics and Experimental Design DESCRIPTION ----------- This essential reference provides veterinary researchers, clinicians, and students with comprehensive guidance on determining appropriate sample sizes for animal-based research studies. Understanding proper sample size calculation is critical for ensuring statistical validity, ethical use of animals, and meaningful research outcomes. This guide demystifies complex statistical concepts and presents practical, step-by-step approaches to calculating sample sizes across diverse study designs commonly encountered in veterinary medicine and animal science research. The book addresses the fundamental principles of statistical power, effect size, and variability while providing species-specific considerations for companion animals, livestock, laboratory animals, and wildlife. Readers will find detailed explanations of sample size determination for various study types including clinical trials, observational studies, diagnostic test evaluations, and experimental research. The text emphasizes the ethical imperative of using the minimum number of animals necessary to achieve scientifically valid results, aligning with the principles of the Three Rs (Replacement, Reduction, and Refinement). Practical examples, case studies, and worked calculations throughout the book enable readers to apply these principles directly to their own research projects. Whether planning a small pilot study or a large multi-center clinical trial, this guide equips veterinary professionals with the statistical knowledge and practical tools needed to design robust, ethically sound animal studies that yield reliable, publishable results. KEY FEATURES ------------ • Comprehensive coverage of sample size calculation methods for diverse veterinary study designs including randomized controlled trials, cohort studies, case-control studies, and crossover designs • Species-specific considerations and examples covering companion animals, farm animals, laboratory animals, exotic species, and wildlife populations • Practical guidance on determining effect sizes, estimating variability, and selecting appropriate statistical power levels for veterinary research • Step-by-step calculation examples with clear explanations of underlying statistical principles, making complex concepts accessible to non-statisticians • Ethical considerations for minimizing animal use while maintaining scientific rigor and statistical validity in accordance with animal welfare regulations • Guidance on sample size adjustments for anticipated dropout rates, clustering effects, and multiple comparison procedures • Ready-to-use tables, formulas, and decision trees for quick reference during study planning and grant proposal preparation TARGET AUDIENCE --------------- • Veterinary researchers and principal investigators designing animal-based studies for academic, pharmaceutical, or government research institutions • Graduate students in veterinary medicine, animal science, and comparative medicine programs conducting thesis or dissertation research • Clinical veterinarians planning prospective clinical studies or participating in multi-center veterinary clinical trials • Institutional Animal Care and Use Committee (IACUC) members reviewing research protocols for scientific and ethical adequacy • Biostatisticians and research coordinators supporting veterinary and animal science research programs INSTANT ACCESS -------------- Download immediately after purchase Compatible with all PDF readers Personal use license included PRICE: HK$220.00